Fig. 1: Motivation, rationale, and development of rhodaelectro-catalyzed annulation of benzaldehydes. | Nature Communications

Fig. 1: Motivation, rationale, and development of rhodaelectro-catalyzed annulation of benzaldehydes.

From: Rhodaelectro-catalyzed access to chromones via formyl C–H activation towards peptide electro-labeling

Fig. 1

a Chromones as a privileged motive in pharmaceutical and bioactive compounds. b Strategy to access chromones via rhodaelectro catalysis and its use for electro-peptide labeling. c Synthesis of rhodium complex Rh-I and investigations of its redox properties by cyclic voltammetry in CH2Cl2 with nBu4NPF6 (0.2 M). d Reaction development, 0.25–0.50 mmol scale, 4.0–8.0 mL solvent, isolated yields. aWith nBu4NPF6 (0.1 M) for 4 h. Cp* pentamethylcyclopentadienyl, NaOPiv sodium pivalate, Fc ferrocene, GF graphite felt electrode, CCE constant current electrolysis, CPE constant potential electrolysis, tAmylOH 2-methyl-2-butanol.

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