Fig. 3: Induction of inflammatory mediators are strongest and earliest in myeloid cells.
From: Temporal omics analysis in Syrian hamsters unravel cellular effector responses to moderate COVID-19
Dotplots of differentially expressed cytokines and inflammatory mediators in lungs. Shown are genes that display a significant absolute log2-transformed fold change of at least one in at least one comparison, and are grouped into four categories indicated on the left. Coloration and point size indicate log2-transformed fold changes (FC) and p-values, respectively, of genes at 2 days post infection (dpi) relative to control groups (naive). Adjusted (adj) p-values were calculated by DEseq2 using Benjamini–Hochberg corrections of two-sided Wald test p-values. Genes are ordered by unsupervised clustering, cell type as in Fig. 1.
