Fig. 3: C-Mannosylation of alkyne derivatives of amino acids and peptides. | Nature Communications

Fig. 3: C-Mannosylation of alkyne derivatives of amino acids and peptides.

From: Facile access to C-glycosyl amino acids and peptides via Ni-catalyzed reductive hydroglycosylation of alkynes

Fig. 3

1a (0.1 mmol), 2 (2.0 equiv.), NiCl2(DME) (10 mol%), dtbbpy (12 mol%), PPh3 (20 mol%), DEMS (2.5 equiv.), Na2CO3 (2.5 equiv.), DME/DMAc (10/1, v/v, 1 mL), 25–35 °C, Ar, 36 h. Isolated yields are reported. In red are the formed C-glycosidic bonds.

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