Table 2 Structural features of the mRNAs that are most upregulated.

From: The pathogenesis of mesothelioma is driven by a dysregulated translatome

Description

  

P value

shorter 5′-UTR

t test

***

2.805E-08

higher 5′-UTR MFE

t test

***

1.558E-11

fewer uORF

χ2

***

1.096E-07

TISU elements

χ2

***

6.074E-06

TOP/TOP like

χ2

ns

 

AU-rich elements

χ2

ns

 
  1. These included upstream open-reading frame (uORF) = 833; terminal oligopyrimidine tract TOP/TOP-like = 126; AU-rich elements =  297; translation initiator of short 5′-UTR, TISU = 28 MFE = minimum-free energy.
Back to article page