Fig. 7: Controlled experiments.
From: Biomimetic approach to the catalytic enantioselective synthesis of tetracyclic isochroman
Unless otherwise noted, all reactions were carried out on a 0.2 mmol scale with 1 eq 2b, 1.2 eq 3a or 10, 10 mol% of Sc(OTf)3, 11 mol% of L-PiMe2t-Bu and 5 mol% of JohnphosAu in DCM (2.0 mL) under 6 °C.
