Fig. 6: Detected enzymes, metabolites, and associations in the histidine metabolism pathway (KEGG KO00340). | Nature Communications

Fig. 6: Detected enzymes, metabolites, and associations in the histidine metabolism pathway (KEGG KO00340).

From: Gut microbiome-mediated metabolism effects on immunity in rural and urban African populations

Fig. 6

Colored nodes represent detected microbial enzymes (squares) and compounds (circles), with significant correlations with cytokine responses in red (positive) and blue (negative). Enzymes detected in stool microbiomes are shown as colored squares, with contribution from negative (blue) or positive species (red) quantified as a fraction of total RPKM in the cohort per species type. Percentages in squares show prevalence of enzyme encoded by each species. Source data are provided in the Source data file.

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