Fig. 4: Boolean functions implemented on a dual-unit 3D DNA nanostructure system.
From: DNA dynamics and computation based on toehold-free strand displacement

a Schematic diagram of ON/OFF binding switch of two cuboid origami units (8H × 8H × 10T): the binding of cuboids I and II in the absence of blockers (as ON) and the displacement in the presence of blockers (as OFF). b–e Boolean function of 4-bit input and 2-bit output. 4-bit input comprises system state of 2 bits (NN* and MM*) of two units and controller of 2 bits (blockers N’ and M’). 2-bit output is read out as the resulted shapes (multimer, dimer or monomer) under TEM. Scale bars: 50 nm.