Fig. 3: Comparison of nanobody-RBD complexes. | Nature Communications

Fig. 3: Comparison of nanobody-RBD complexes.

From: A potent SARS-CoV-2 neutralising nanobody shows therapeutic efficacy in the Syrian golden hamster model of COVID-19

Fig. 3

a Superimposition of H11-H4-RBD and H3-RBD complexes; V102 is shown by a red sphere. b Overlay showing the key salt bridge interaction between E484 in RBD and R31 in nanobody H3 and R52 in nanobody C5, respectively. c Close-up of the RBD-C5 interfaces for complexes with the Victoria strain of SARS-CoV-2 (N501: left hand side) and Alpha strain (N501Y: right hand side) showing the hydrogen bonding between N501 and Y501 of RBD (coloured green) with N73 of C5 in yellow and wheat respectively. Key residues are shown in stick representations.

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