Fig. 5: Performance of DEEP Picker for selected regions of 2D 15N–1H HSQC spectrum of α-synuclein. | Nature Communications

Fig. 5: Performance of DEEP Picker for selected regions of 2D 15N–1H HSQC spectrum of α-synuclein.

From: DEEP picker is a deep neural network for accurate deconvolution of complex two-dimensional NMR spectra

Fig. 5

A–C HSQC spectrum processed with original resolution and D–F with reduced resolution along indirect dimension. Three pairs of panels (A, D), (B, E), (C, F) show the same 2D regions for comparison. Picked cross-peaks are indicated as circles and color-coded according to their amplitude on a logarithmic scale, whereas the contour line spacings are linear. Despite the lower spectral resolution in D–F, DEEP correctly picked the peaks, including all strongly overlapped cross-peaks. Note that the spectra of Panels D–F have reduced sensitivity since they used only half of the time-domain data.

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