Fig. 6: Identification of undocumented xenobiotic exposures.
From: Large scale enzyme based xenobiotic identification for exposomics
a Heatmap of relative peak intensities of related xenobiotics in 120 humans (each column from left to right represents an individual sample) with paired urine and plasma samples. Metabolites were detected at the same accurate mass m/z and retention time as S9-enzyme generated metabolites. Relative abundance values were colored across each row using the maximum observed peak intensities (red) and minimum observed peak intensities (blue) for a particular metabolite. b MS2 spectra of selected metabolites (nicotine, hydroxynapthalene sulfate, omeprazole, piperine) in experimental sample (black) compared with S9-reactions (red).
