Fig. 2: Methylation group-based classification of RIG.
From: Comprehensive molecular characterization of pediatric radiation-induced high-grade glioma
a Circular dendrogram indicating the location of RIG (black bars) relative to reference CNS tumors. b Localization of RIGs relative to other CNS cancers in t-SNE space (legend shown below). c Dendrogram and heatmap of RIG cases clustered against reference CNS tumors (legend to right). A-IDH astrocytoma, subclass IDH-mutant, A-IDH-HG high-grade astrocytoma, subclass IDH-mutant, ANA PA anaplastic pilocytic astrocytoma, CONTR-CEBM control cerebellum, CONTR-HEMI control cerebral cortex, DMG-K27 diffuse midline glioma, H3K27M-mutant, GBM-G34 glioblastoma, subclass H3.3 p.G34R-mutant, GBM-MES glioblastoma, subclass mesenchymal, GBM-MID glioblastoma, IDH-wild type, subclass midline, GBM-MYCN glioblastoma, subclass MYCN-amplified, GBM-RTK-I, adult glioblastoma, subclass RTK I, GBM-RTK-II adult glioblastoma, subclass RTK II, GBM-RTK-III adult glioblastoma, subclass RTK III, HGNET-MN1 high-grade neuroepithelial tumor with MN1 alteration, IHG infantile high-grade glioma, pedRTK I pediatric glioblastoma, subclass RTK I, pedRTK II pediatric glioblastoma, subclass RTK II, PXA pleomorphic xanthoastrocytoma, RIG radiation-induced high-grade glioma, t-SNE t-distributed stochastic neighbor embedding.
