Fig. 4: Correlation between clinical outcomes and sequencing data.

a The core-enriched signaling pathways. Normalized enrichment score (NES suggested the results across the analyzed genes. b Dot plot showing the genes associated with the clinical indexes related to coagulation function, myocardial enzymes, and inflammation (Pearson correlation coefficient (r), and two-sided t-tests). c Fold changes of laboratory results from 41 patients infected with SFTSV at admission are shown on the graphs. The fold changes are calculated according to the following formula: Fold changes = (A−B)/B (A indicates the clinical testing results at admission, B represents the up or low limit of the normal ranges, n = 41 patients, error bars represent standard error of means (SEM)). LAPTT activated partial thromboplastin time, TT thrombin time, FIB fibrinogen, DD D-dimer, AST aspartate aminotransferase, CK creatine kinase, CKMB creatine kinase MB, MYO myoglobin, LDH lactate dehydrogenase, HSTNI hypersensitive troponin I, CRP C-reactive protein, PCT procalcitonin.