Fig. 1: Patient characteristics and tumor location.
From: Parity associates with chromosomal damage in uterine leiomyomas
a Patient characteristics (N = 628). The distribution of the number of tumors per patient, parity, the age of the patients, and menopause status. Median is shown by blue vertical line. b Intramural, subserous, and submucous locations of uterine leiomyomas (ULs) (N = 1451). The majority of the tumors are intramural, but MED12 mutated tumors are associated with subserous location. c On the top left, age at hysterectomy stratified by parity. The y-axis is in years. Boxplots show the median and the first and third quartiles. Error bars extend up to 1.5 IQR above the quartiles. The number of patients in each class is: parity 0 = 196, 1 = 108, 2 = 213, 3 = 71, 4 = 28, 5 = 9, 6 = 1, 7 = 1. On the bottom left, the number of patients with a history of ever smoking (yes/no) stratified by parity. On the top right, the number of patients with combined oral contraceptives use (ever/never) stratified by parity. On the bottom right, the number of pre-menopausal, post-menopausal patients and patients with hormonal replacement therapy (HRT). Source data are provided.
