Fig. 5: Stromal composition associated with metastatic tumor thrombus.
From: Determinants of renal cell carcinoma invasion and metastatic competence
a Differentially expressed genes between TTNM and TTM and their prognostic power based on human protein atlas. b Quantification and representative immunohistochemistry images of endothelial marker ERG in TTNM and TTM sections (n = 20 patients, 36 samples). c Quantification and representative immunohistochemistry images of macrophage marker CD163 in TTNM and TTM sections (n = 20 patients, 36 samples). Data are presented as scatter dot plots and lines at mean values ±SEM; two-tailed Mann-Whitney U-test (b, c). d TIMER analysis using a QUANTIFSEQ deconvolution-based approach revealing differences in stromal composition from biologically independent TTNM (n = 78) and TTM (n = 82) patient (tumor samples). Two-sided unpaired Student t test.
