Fig. 6: Core matrisome recapitulation in PDX, PA-ECM and organoid models.
From: Bioengineered 3D models of human pancreatic cancer recapitulate in vivo tumour biology
a Heatmap of the top matrisome proteins detected which fall on or above the 90th percentile rank in abundance (mean across all patients) in at least one of the sample categories. For the PDX and Matrigel samples, abundance was calculated as the sum of the human and murine peptides. Those proteins for which >50% of the peptides detected were of murine origin are indicated with an asterisk. b Distribution of interstitial collagen chains and laminin trimers for all sample categories. Data correspond to the mean across all patients.
