Table 3 Clinical validation of gene classifier. Gene classifier (as described in Results section and Fig. 2a) was tested for prediction of response to anti-PD1 treatment. PPV positive predictive value, NPV negative predictive value.
Spatial immunophenotype (gene-classifier) | ||||
---|---|---|---|---|
Excl & Ign | Infl | Total | ||
Anti-PD1 treatment | Nonresponder | 35 | 4 | 39 |
Responder | 4 | 6 | 10 | |
Total | 39 | 10 | 49 | |
NPV | 0.9 | |||
PPV | 0.6 |