Table 3 Clinical validation of gene classifier. Gene classifier (as described in Results section and Fig. 2a) was tested for prediction of response to anti-PD1 treatment. PPV positive predictive value, NPV negative predictive value.

From: Spatial immunophenotypes predict response to anti-PD1 treatment and capture distinct paths of T cell evasion in triple negative breast cancer

 

Spatial immunophenotype (gene-classifier)

 

Excl & Ign

Infl

Total

Anti-PD1 treatment

Nonresponder

35

4

39

Responder

4

6

10

Total

39

10

49

NPV

0.9

 

PPV

0.6