Fig. 2: Evaluation of reaction conditions for the migratory allylic substitution.
From: Palladium-catalyzed regio- and enantioselective migratory allylic C(sp3)-H functionalization
aThe reactions were run with 2a (0.2 mmol), NaBArF4 (ArF = 3,5-(CF3)2Ph, 5 mol%) in solvent (0.2 mL). Yields were determined by crude 1H NMR. Er values were determined by chiral HPLC. THF, tetrahydrofuran. CPME, cyclopentyl methyl ether. bIsolated yield.
