Fig. 2: Comprehensive characterization of representative neutralizing mAbs 7D6, 6D6, and 16D8.
From: Cross-neutralizing antibodies bind a SARS-CoV-2 cryptic site and resist circulating variants
a–c Neutralization of three mAbs by LV-SARS-CoV-2 (a), LV-SARS-CoV (b), and VSV-SARS-CoV-2 (c). d Neutralization activities of three mAbs to authentic SARS-CoV-2. e SPR kinetics and the affinities of three antibodies to S-2P and RBD proteins of both SARS-CoV-2 and SARS-CoV. f SPR-based blocking assays of the three mAbs perturbing the engagement of ACE2 to RBD. g Inter-blocking potentials of the three mAbs. Data in a, b, d are presented as mean values ± SEM. Source data are provided as a Source Data file.
