Fig. 3: T-DM1 and RAB GTPase in vitro correlations.
From: RAB5A expression is a predictive biomarker for trastuzumab emtansine in breast cancer
Linear regression analysis curves between RAB5A (A), RAB4A (B), and RAB11A (C) protein expression (average of N = 3 as presented in Fig. 2) and T-DM1 sensitivity (1/IC50(T-DM1)) (average of N = 3 as presented in Fig. 1 and Table 1) in the five cell lines. D The linear regression curve between HER2 (average of N = 3 as presented in Fig. 2) × RAB5A protein expression and T-DM1 response. Each data point represents one cell line. Source data are provided as a Source Data file.
