Fig. 1: Consort diagram for the T-DM1/Pertuzumab, THP, and control populations.

Consort diagram shows the number of patients screening, randomized, and receiving allocated therapy from the start of I-SPY2 to the close of the T-DM1/Pertuzumab and THP arms. I-SPY2 is modified intent-to-treat, where patients receiving their allocated therapy are considered evaluable for analysis.