Fig. 4: VAR2CSA-specific IgG induced by subunit vaccination is not Fc afucosylated. | Nature Communications

Fig. 4: VAR2CSA-specific IgG induced by subunit vaccination is not Fc afucosylated.

From: Afucosylated Plasmodium falciparum-specific IgG is induced by infection but not by subunit vaccination

Fig. 4

Fc fucosylation levels of total (gray) and VAR2CSA-specific (orange) plasma IgG1 in German vaccinees (n = 32) without (a) and in Beninese vaccinees (n = 18) with (b) natural exposure to P. falciparum. Medians and densities are shown. Statistically significant pairwise differences between antigen-specific IgG and total IgG (two-sided Wilcoxon signed-rank test) are indicated (****P < 0.0001).

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