Fig. 3: Structure of EF-G–GDP–Pi in H1 state.
From: Structural mechanism of GTPase-powered ribosome-tRNA movement
Panels 1–4 depict distinct regions as indicated in the overview (middle left) with EF-G D1–D5 and sw1. Panel 1: Pi coordinates a network of interactions that stabilize the compact sw1 structure. Panel 2: interaction with EF-G–GDP–Pi induces a unique SRL twist. Panel 3: compacted sw1 bridges between LSU and SSU, thereby stabilizing the rotated state. Panel 4: interactions of EF-G D2 and sw1 with the rotated SSU body domain.
