Fig. 3: Substrate scope of N-tosyl amines.
From: Ni-catalyzed hydroalkylation of olefins with N-sulfonyl amines
Reaction conditions: N-sulfonyl amine 1 (0.2 mmol), 2a (0.4 mmol), Ni(cod)2 (2.5 mol%), PCy3 (5 mol%), PhB(OH)2 (25 mol%), KOtBu (25 mol%), toluene (0.3 mL), N2, 120 °C; isolated yields were reported. aNi(cod)2 (5 mol%), PCy3 (10 mol%). bPhB(OH)2 (100 mol%), KOtBu (50 mol%). cPivaldehyde (2.0 equiv.) was added. dNi(cod)2 (5 mol%), PCy3 (10 mol%), PhB(OH)2 (100 mol%), KOtBu (100 mol%). Bz, benzoyl, Et ethyl, Boc tert-butyloxycarbonyl.
