Fig. 2: Poly-α-peptoids displayed an excellent in vitro antibacterial profile.
From: Addressing MRSA infection and antibacterial resistance with peptoid polymers
a Antibacterial activity of Poly-α-peptoids. b Chemical structure of HS(Naeg)n and GPC characterization of N-Cbz protected HS(Naeg)n (n = 5, 10, 20, 40). c MIC values of HS(Naeg)n, at variable chain length, against S. aureus ATCC6538 using magainin II for comparison. d Hemolysis of HS(Naeg)20 and HS(Naeg)40 on human red blood cells. e Selectivity index calculated from HC50/MIC. f Cytotoxicity of HS(Naeg)20 and HS(Naeg)40 on fibroblast cells. g Selectivity index calculated from IC50/MIC.
