Fig. 1: Overview of the mouse brain atlas dataset.

a Graphic illustration of the workflow to acquire aging mouse brain metabolome data. b Chemical composition of the mouse brain metabolome using ClassyFire categories to classify the metabolite diversity of all annotated metabolites across assays. c Number of annotated metabolites by metabolome assay and brain regions. d Mapping polar metabolites assayed by HILIC- and GC–MS to pathways. Top-10 mapped pathway-based sets shown from a total of 118 pathways covered by Consensus PathDB.