Fig. 4: Evolutionary history of benzylisoquinoline alkaloid (BIA) gene cluster.

a The syntenic relations at BIA gene cluster in three Papaver species. Solid lines denote the syntenic relations detected by MCScanX, and the dash lines denote the top BlastP hits. Different colors denote different genes. The gene name or ID is labeled for each gene. The numbers above the genes represent sequence identity levels from BlastP. The directions of arrows indicate the chromosome from 5′ to 3′. BH best hit. b Summary of BIA gene cluster evolution. Putative tandem duplication as a structural variation event producing identical adjacent segments while the other non-locally duplicated ones are “putative dispersed duplication”. MRCA most recent common ancestor, WGD whole-genome duplication, Mya million years ago. Source data underlying a are provided as a Source Data file.