Fig. 4: Signatures of polygenic selection on CTMAX-associated SNPs. | Nature Communications

Fig. 4: Signatures of polygenic selection on CTMAX-associated SNPs.

From: Selection on adaptive and maladaptive gene expression plasticity during thermal adaptation to urban heat islands

Fig. 4

Extended linkage disequilibrium (≥5 kb) is observed in CTMAX-associated SNPs (red) in comparison to the transcriptome-wide background (gray) (linear mixed-effects model: p < 0.05) in both forest (Column 1) and urban (Column 2) habitats, suggesting ongoing selection on thermal physiology island-wide. In addition, increased genetic divergence between urban and forest habitats (Column 3) in CTMAX-associated SNPs (red) with respect to background (gray) expectations (Arecibo, Mayagüez, and San Juan: Welch t-test; p < 0.05 (asterisks)) supports selection on heat tolerance specific to urban heat islands. LD plots are represented in 1 kb distance bins. Dots and error bars represent means ± 1 SE. All 130 animals for which we had sequence data were used for this analysis.

Back to article page