Fig. 7: Characterization of endothelial cells in PTCs.

a t-SNE projection showing five different subtypes of ECs. Expression levels of marker genes for arterial (b), venous (c), lymphatic (d), immature (e), and tip ECs (f). g Heatmap showing the TF activities in the five EC subtypes, scored by SCENIC and AUCell. h Sankey diagram showing assignment of normal EC (NEC) and tumor EC (TEC) to arterial, venous, lymphatic, immature and tip subtypes. i Bubble plots showing L-R pairs of cytokines, chemokines and growth factors between tip ECs and other cell types, inferred by CellPhoneDB. Source data are provided in the Source data file.