Table 2 COVA1-18 and COVA1-16 neutralization potency against variants in HEK293T hACE2 cells.

From: COVA1-18 neutralizing antibody protects against SARS-CoV-2 in three preclinical models

 

IC50 (ng ml−1)

COVA1-18

COVA1-16

COVA1-18 + COVA1-16 (1:1)

Wild type

1.7

80.7

N/A

D614G

0.7

109.2

1.0

B.1.1.7

1.4

90.8

2.2

E484K

>12500

94.3

N/A

B.1.351

>50000

50.6

97.6

  1. Mean IC50 values with n ≥ 3, except for the cocktail with n = 2. N/A, not assessed.
Back to article page