Fig. 2: Characterization of subsets for NK, NKT, and B cells based on marker gene expression. | Nature Communications

Fig. 2: Characterization of subsets for NK, NKT, and B cells based on marker gene expression.

From: Dysregulation of TFH-B-TRM lymphocyte cooperation is associated with unfavorable anti-PD-1 responses in EGFR-mutant lung cancer

Fig. 2

a UMAP and mosaic plots for NK and NKT cells. The p-value shown in the mosaic plot was obtained from a one-sided Chi-square test. b, c Violin plots for the expression of genes involved in activation (b) and cytotoxicity (c) of NK or NKT lymphocytes across subsets (H, high expression level; L, low expression level). Each subset was characterized based on the expression levels of genes involved in activation and cytotoxicity. For example, NKT-C7 was characterized by low activation and high cytotoxicity. d UMAP and mosaic plots for B cells. e Violin plots for the expression of genes involved in antigen presentation and processing in B cells of EGFR-WT or EGFR-MT tumor.

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