Table 2 Median flashfm running time (with second and third quartiles), in seconds.

From: The flashfm approach for fine-mapping multiple quantitative traits

Number of Traits

250-SNP Region (67 kb)

500-SNP Region (144 kb)

1000-SNP Region (312 kb)

2

2 (1, 7)

5 (2, 15)

5 (1, 16)

3

13 (5, 33)

15 (8, 40)

16 (5, 59)

4

435 (49, 2173)

583 (116, 1790)

168 (32, 740)

  1. Flashfm was run using cpp = 0.99 and single-trait fine-mapping results from JAM, using the extended version (JAMexpandedCor.multi) in the flashfm package. Median time was measured over 100 replications in simulations of 2, 3, and 4 traits having correlation 0.4 and sample size 5000. The regions were subsets of the CTLA4 region 2q-204446258-204816382 (GRCh37/hg19).
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