Table 2 Posterior mean and 95% credibility intervals for anti-spike IgG peak level (intercept) (ng ml⁻¹) and half-life (slope) (days) in the univariable and multivariable models in 3271 participants in Class 1.

		Univariable model			Multivariable model
		Posterior mean	95% Crl		Posterior mean	95% Crl
Baseline	Peak level (Intercept) (ng ml⁻¹)	203	190	210	185	157	201
	IgG half-life (slope) (days)	184	163	210	233	161	364
Age	Peak level: 43 years (median)	200	187	206
	IgG half-life: 43 years (median)	204	177	237
	Change in peak level: per 10-year older	17	13	22	18^a	13	23
	Change in half-life: per 10-year older	−2	−20	21	−8	−36	23
Sex	Peak level: female	199	183	209
	IgG half-life: female	232	189	291
	Change in peak level: male	8	−6	21	6	−7	19
	Change in half-life: male	−79	−141	−30	−77^a	−178	−23
Ethnicity	Peak level: White	197	184	204
	IgG half-life: White	190	166	219
	Change in peak level: non-White	70	40	99	82^a	55	113
	Change in half-life: non-White	−46	−92	13	−75^a	−181	−1
Long-term health conditions	Peak level: no	198	182	206
	IgG half-life: no	186	163	213
	Change in peak level: yes	24	6	43	13	−2	30
	Change in half-life: yes	11	−50	100	10	−93	162
Ct value	Peak level: 22 (median)	202	190	209
	IgG half-life: 22 (median)	184	163	209
	Change in peak level: per 1 unit higher	1	0	2	1^a	0	2
	Change in half-life: per 1 unit higher	0	−4	4	0	−7	7
Symptom	Peak level: no	205	180	221
	IgG half-life: no	154	124	197
	Change in peak level: yes	−3	−20	14	1	−14	16
	Change in half-life: yes	41	−8	86	57	−64	172

The reference category in the multivariable model is: 43-year-old, female, White ethnicity, no long-term health conditions, Ct value = 22, and no self-reported symptoms.
^aWhere the multivariable 95% CrI excludes 0 (no effect).

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