Fig. 2: Comparison of the structures of Si channel Lsi1 and other AQPs.
From: Structural basis for high selectivity of a rice silicon channel Lsi1
Superposition of the structure of Lsi1cryst (cyan) with AQP1 (pink, PDB 1J4N) (a), and GlpF (light green, PDB 1FX8) (b). Top view from the extracellular side (left) and a rotated view by 45° against the membrane normal (right). Arrowheads indicate loop A and red arrows represent the shift of TM helices (in Å). A diamond shape represents a pseudo-C4 symmetric axis. Channel profile (c) and diameters (d) along the pore for Lsi1cryst, AQP1, and GlpF, calculated using the program HOLE2, are shown. The regions for SF and NPA motifs are colored in plum and khaki, respectively. An arrowhead indicates the distortion in the channel. e Cross-section of the channel of Lsi1cryst, Aqy1 (wheat, PDB 3ZOJ), and GlpF with a 55° rotation relative to (c). Water molecules in the channel (red), extra/intracellular regions (pink), and glycerol molecules are shown. In e, N-terminal and C-terminals of Aqy1 were omitted for clarity. The color coding shown here is used for all Figures unless otherwise noted.
