Fig. 1: The neutralizing capabilities of the top 10 mAbs against authentic SARS-CoV-2 and B.1.351 viruses.

The neutralizing potency of the top 10 mAbs was measured by authentic SARS-CoV-2 (nCoV-SH01) neutralization assay and quantified by a qRT-PCR (n = 3 biologically independent samples) or authentic SARS-CoV-2 (WIV04) and B.1.351 neutralization assays and quantified by b plaque-reduction neutralization testing (PRNT) (n = 2 biologically independent samples). Data were presented as a mean values ± SEM and b mean values. The IC50s were summarized in c. Dashed line indicated 0% or 50% reduction in viral neutralization. Effective Abs against authentic B.1.351 were shown in bold.