Fig. 5: One-step modification of hydrogels to have antibacterial property.
From: A sandcastle worm-inspired strategy to functionalize wet hydrogels
a A schematic diagram for antibacterial test of hydrogels from direct modification with DbaYKY terminated antibacterial polymers, Pol-1 and Pol-3. Antibacterial tests were performed by incubating 40 μL bacterial suspension (2 × 106 CFU/mL) on top of the hydrogels for 2.5 h. b Bacterial killing efficacy of Pol-1 and Pol-3 functionalized hydrogels against E. coli and S. aureus. n = 3, mean values ± s.d. c Images of E. coli and S. aureus colonies on the LB agar plates correlating to surviving bacteria on the surface of bare hydrogel and functionalized hydrogels. LB agar and antibiotic-loaded LB agar (1 mg/mL vancomycin for S. aures and 1 mg/mL polymyxin B for E. coli) were used as the negative control and the positive control, respectively. d Durability test on the bacterial killing efficacy of Pol-1 and Pol-3 functionalized hydrogels against E. coli and S. aureus. n = 3, mean values ± s.d. The antibacterial tests were performed using hydrogels that were initially incubated with bacterial solution for 1 day, 3 days, and 7 days.
