Fig. 7: One-step modification of hydrogels to promote wound healing.
From: A sandcastle worm-inspired strategy to functionalize wet hydrogels
a Photographs of wounds on day 0, 3, 6, 9, and 12 after treatment with bare PVA hydrogels and Pol-7 modified PVA hydrogels. Scale bar: 5 mm. b Schematic diagram of wound healing process from day 0 to day 12 after treatment with bare PVA hydrogels and Pol-7 modified PVA hydrogels. c Wound closure rate after treatment with bare PVA hydrogels or Pol-7 modified PVA hydrogels. n = 6, mean values ± s.d. Statistical analysis: one-way ANOVA with Tukey’s post-test, #P < 0.05, *P < 0.01. d H&E staining of wound tissue on day 12 after treated with bare PVA hydrogels or Pol-7 modified PVA hydrogels. Scale bar: 500 µm. Wounds without hydrogel treatment were used as the blank control in all above studies (a–d).
