Fig. 6: Examples of unsuccessful palladiumd-catalyzed asymmetric umpolung difluoroallylation. | Nature Communications

Fig. 6: Examples of unsuccessful palladiumd-catalyzed asymmetric umpolung difluoroallylation.

From: Regio- and enantioselective umpolung gem-difluoroallylation of hydrazones via palladium catalysis enabled by N-heterocyclic carbene ligand

Fig. 6

a Palladium-c-atalyzed reaction of N-tert-Bu hydrazone 1aa with BDFP. b Palladium-catalyzed reaction of hydrazone 1z with BDFP using L8 as the ligand. c Palladium-catalyzed reaction of hydrazone 1a with (E)-1-bromo-1,1-difluorooct-2-ene (2b). d Palladium-catalyzed reaction of hydrazone 1a with (3-(bromodifluoromethyl)but-3-en-1-yl)benzene (2c).

Back to article page