Fig. 1: CaMKIIδc interacts with NaV1.8 in human myocardium and isolated cardiomyocytes.

a Co-immunoprecipitation of CaMKIIδc and NaV1.8 from left ventricular homogenates of human non-failing and failing hearts (NF: n = 7; HF: n = 7). b Co-localization of CaMKIIδc and NaV1.8 in human failing cardiomyocytes with immunofluorescence staining. Scale bar: 10 µm (staining was performed in cardiomyocytes isolated from five heart failure patients).