Fig. 6: Functional recovery of a mouse stroke model by a single injection of JigSAP nanofibers incorporating VEGF-JigSAP proteins.

Ratios of fault steps to total steps during FFT. a dMCAO model. b photothrombotic model. *P < 0.05 (Student’s t-test against VEGF-JigSAP + JigSAP, two-sided). n = 7. Box-plot elements show: center line, median; box limits, 25 and 75 percentiles; whiskers, (Q1/4–1.5IQR) and (Q3/4–1.5IQR). Source data are provided as a Source Data file. Abbreviations; dMCAO (distal middle cerebral artery occlusion), PT (photothrombotic model), PBS (phosphate buffered saline), VEGF (vascular endothelial growth factor), JigSAP (jigsaw-shaped self-assembling peptide).