Fig. 1: Overall structure. | Nature Communications

Fig. 1: Overall structure.

From: Structural basis of the regulation of the normal and oncogenic methylation of nucleosomal histone H3 Lys36 by NSD2

Fig. 1

Unless stated otherwise, proteins are colored as follows: NSD2, magenta; H3, blue; H4, green; H2A, pink; and H2B, yellow. a Density map and b ribbon model, two views related by 180° rotation. c Superposition of the current NSD2-nucleosome structure with that of a canonical nucleosome (PDB 1KX5). Duplex DNA in the NSD2 complex stretches straight up to approximately SHL +5.5, resulting in its partial unwrapping.

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