Fig. 3: TF footprinting and analysis. | Nature Communications

Fig. 3: TF footprinting and analysis.

From: Cis-regulatory architecture of human ESC-derived hypothalamic neuron differentiation aids in variant-to-gene mapping of relevant complex traits

Fig. 3

a The summary of TF-binding site prediction, the Purity scores calculated by PIQ (purple/yellow), the number of TF-binding sites passing purity cutoff >0.7 thresholds (Grayscale), log2 transformed expression of the respective TF in HN (white/orange). b Grouping number of TF-binding sites family. Darker color indicates a higher number of predicted binding sites. c–e Enrichment of TF-binding sites in putative cREs compared to other OCRs in each cell type adjusted for GC content and read count.

Back to article page