Fig. 2: Mucosal, spike-specific IgA responses. | Nature Communications

Fig. 2: Mucosal, spike-specific IgA responses.

From: Protective mucosal immunity against SARS-CoV-2 after heterologous systemic prime-mucosal boost immunization

Fig. 2

BALB/c mice were vaccinated according to Fig. 1A. BAL samples were tested for spike-specific IgA directed against the domains of S2 (A), S1 (B), or RBD (C) by ELISA (dilution: 1:10). Bars represent group medians overlaid with individual data points; naïve n = 4; DNA-Ad5 n = 5; other groups n = 6. Data were analysed by one-way ANOVA followed by Tukey’s post test. Statistically significant differences are indicated only among the different vaccine groups; p values indicate significant differences (*p < 0.05; **p < 0.005; ***p < 0.0005; ****p < 0.0001).

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