Fig. 6: Neutralization of SARS-CoV-2 variants. | Nature Communications

Fig. 6: Neutralization of SARS-CoV-2 variants.

From: Protective mucosal immunity against SARS-CoV-2 after heterologous systemic prime-mucosal boost immunization

Fig. 6

C57BL/6 mice were vaccinated according to Fig. 5A. BAL samples were analysed by pseudotype neutralization assays for the neutralization of different SARS-CoV-2 variants (A–E). Data points were shown for individual animals and bars represent group medians; RNA-Ad5 n = 7, other groups n = 8 (out of two independent experiments). The dashed line indicates the lower limit of detection. Data were analysed by Kruskal–Wallis test (one-way ANOVA) followed by Dunn’s multiple comparison. Statistically significant differences are indicated only among the different vaccine groups; p values indicate significant differences (*p < 0.05; **p < 0.005; ***p < 0.0005; ****p < 0.0001).

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