Fig. 6: Gemfibrozil indirectly targets the intersection of disease modules.
From: Network medicine for disease module identification and drug repurposing with the NeDRex platform
The AD and hyperlipidemia disease modules (top left and top right, respectively) derived by DIAMOnD using the corresponding disease-associated genes (orange nodes). The intersection of the disease modules is shown in the middle. Gemfibrozil indirectly targets the intersection through TTR, CYP2C8, and LPL (bottom). To allow better visualisation, subsets of actual networks corresponding to the disease modules are shown here.
