Fig. 4: µMS screen of g2ps1 mutant library for increased production of TAL or AHP. | Nature Communications

Fig. 4: µMS screen of g2ps1 mutant library for increased production of TAL or AHP.

From: Mapping enzyme catalysis with metabolic biosensing

Fig. 4

a Normalized m/z intensity for m/z 127 (TAL) versus 169 (AHP). Data points are colored based on clusters identified from UMAP analysis in Fig. 2. Inset shows reference strain samples. The highest producers for TAL and AHP were isolated, sequenced, and confirmed in bulk analysis (black circles). b TAL and AHP for selected bulk cultures as fold change over wild type (TLML). n = 3 independent experiments. Bar plots represent mean values, with black dots representing each measurement of the samples. Source data are provided as Source Data and raw data in Supplementary Data 5 and 6.

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