Fig. 3: The genomic correlates of TERT abundance.

a Correlation of TERT RNA abundance with tumour telomere length (TL) and TL ratio. Spearman’s ρ and P-values are displayed, two-sides. b–e Correlation of TERT abundance and b the number of GRs, c number of SNVs, d number of indels and e PGA. Spearman’s ρ and P-values are displayed, two-sided. f Spearman’s correlation of significantly associated methylation probes with RNA abundance and tumour TL. Probes within the promoter are labelled in red while the rest are located in the gene body. Dot size indicated the magnitude of correlation. Background colour indicates unadjusted P-values. Methylation probes are ordered by their correlation between TERT RNA abundance from negative to positive.