Fig. 3: Phospholipid biosynthesis and other top-ranking differential pathways. | Nature Communications

Fig. 3: Phospholipid biosynthesis and other top-ranking differential pathways.

From: High-throughput mediation analysis of human proteome and metabolome identifies mediators of post-bariatric surgical diabetes control

Fig. 3

a Top-ranking differential pathways. Graph illustrates –log10(p-values) and false discovery rates (FDRs), with bars colored by FDR, from Limma Roast’s Mixed statistic87 (which is one-sided) adjusted with FDRs. b Phospholipid biosynthesis network. Nodes are colored by between-group z-score, whereas unmeasured nodes are colored dark gray. Orientation of triangle also indicates the directionality of regulation. Connections are from the Pathway Commons network. Source data are provided as a Source Data file.

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