Fig. 3: Details of protein–DNA interactions and integration site location on RNA Pol III-transcribed genes.
From: Structural basis of Ty3 retrotransposon integration at RNA Polymerase III-transcribed genes
DNA nucleotides of the tD(GUC)K gene modelled in the Ty3 strand-transfer complex are depicted as solid circles and numbered relative to the TSS. Template and non-template strands of the tDNA are shown in dark and light blue, respectively. Mutation of nucleotide −25 to break the pseudo-symmetry of the TATA-box is outlined in red. The TATA-box is highlighted with a grey box. Ty3 long-terminal repeats (LTRs) are highlighted in red shades. Protein–DNA and protein–protein interactions are indicated with solid and dashed lines, respectively.
