Fig. 2: Cryo-EM reconstruction of the vitreous body ATTR twisted-dimer.
From: Structural basis for transthyretin amyloid formation in vitreous body of the eye
a Side view of the reconstructed 3D map with the indicated half-pitch and helical rise. The two protofilaments in the twisted-dimer are colored cyan and pink, respectively. b Cross-section view of the density map (blue) with the modeled structure. Residues in the two protofilaments are colored in pink and cyan, respectively. c Ribbon drawing of seven layers of the twisted-dimer stack.
