Table 1 iRPE genotyping for risk alleles for CFH, C3, and ARMS2 genes.
From: Epithelial phenotype restoring drugs suppress macular degeneration phenotypes in an iPSC model
CFH (Y402H) rs1061170 (T/T—nonrisk, C/C—risk) | C3 (R102G) rs2230199 (C/C—nonrisk, G/G—risk) | ARMS2 (A69S) rs10490924 (G/G—nonrisk, T/T—risk) | |
|---|---|---|---|
iRPE with CFH(Y/Y) allele | |||
iRPE1 | T/T | C/G | G/T |
iRPE2 | T/T | C/G | G/G |
iRPE3 | T/T | C/G | G/G |
iRPE with CFH(H/H) allele | |||
iRPE4 | C/C | G/G | G/T |
iRPE5 | C/C | G/G | T/T |
iRPE6 | C/C | G/G | G/T |
iRPE7 | C/C | C/G | G/T |
iRPE with CFH(Y/H) allele | |||
iRPE8 | C/T | G/G | G/T |
iRPE9 | C/T | G/G | G/T |
iRPE10 | C/T | G/G | G/T |
